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12 December 2017


Glutathione is a tripeptide consisting of glutamate, cysteine and glycine in its molecule. Reduced glutathione (GSH) involved in many biochemical reactions and the defense mechanism of our body. GSH has a very potent antioxidant activity which is beneficial for our cells, especially for balancing free radical and antioxidant levels. Normally, we can obtain glutathione from both endogenous biosynthesis and food intake. When we are older or are in some physiological conditions, our GSH levels seem to decrease, therefore, glutathione supplementation maybe need. The appropriate use of glutathione has to be recommended by physicians or health specialists.

Health benefits of glutathione
• Act as an important antioxidant, fighting against free radicals
• Play a role in detoxification, removing toxic substances, such as chemicals and drugs
• May prevent neurodegenerative diseases, such as Alzheimer’s diseases and    Parkinson’s disease
• Promotes immune systems, encouraging white blood cells fight against viruses, bacteria, and other pathogens as well as cancer cells
• Inhibits tyrosinase enzyme for melanin pigment synthesis, causing higher stimulating   the pheomelanin (a lighter pigment) formation and lower stimulating eumelanin   (a darker pigment) formation, may cause the skin brightening 

The importance of glutathione monitoring
• Glutathione status can be used for evaluation of wellness or well-being
• Glutathione level should be monitored after high dose or long-term supplementation because it may toxic to liver cells and also retina in our eyes which cause the vision problems

N Health provides the quantitative measurement of glutathione (GSH, GSSG and GSH/GSSG ratio) in blood using High Performance Liquid Chromatography (HPLC) with fluorometric detection which is the most reliable analytical method including high accuracy, precision, specificity and sensitivity.

The test should be under the discretion of a physician.  |  The mentioned test is performed by the laboratory with ISO 15189 certification and lab accreditation.

*This operation schedule is for the test performed at N Health head quarter, Bangkok. **Above turnaround time does not include logistic time. For BDMS network hospitals, please contact N Health laboratory located at your hospitals.

References:   1. Free Radical Biology and Medicine 112 (2017) 360-375.                                                                                                        2. Free Radical Biology and Medicine 93 (2016) 110-117.                                                                                                          3. Neurochemistry International 82 (2015) 10-18.

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