Methyl Isobutyl Ketone (MIBK) is a colorless liquid with a sweet odor. It is flammable and easily volatile. MIBK is usually used as a solvent in many industries for the production of paints, varnishes, lacquers, inks, spray dyes, glues, sealers, nitrocellulose, magnetic tapes and semiconductors as well as for metal degreasing. People who have worked in these industries may occupationally expose to MIBK by the inhalation of vapor or by skin and eye contact of liquid. Inhaled vapor of MIBK may irritate the airway. High concentration of exposure may affect the central nervous system which can cause nausea, vomiting, dizziness, narcosis or insomnia. Direct contact of MIBK may irritate the eyes or skin which can damage the sensory neuron. MIBK is classified in Group 2B as an agent that is possibly carcinogenic to humans by International Agency for Research on Cancer (IARC). N Health Toxicology Center provides the urinary Methyl Isobutyl Ketone (MIBK) testing by Gas Chromatography-Mass Spectrometry with Headspace Sampler (HS-GC-MS) which is the reliable analytical method including high accuracy, precision and sensitivity.